Semester 1

SECOND YEAR FIRST SEMESTER

Course

Immunology

Course code

MLSIM 2144

Total Credits:

4

Theory: 2

Practical: 1

Tutorial: 1

Field:

Independent Learning

Hours: 123

Credit Hours

Theory: 30

Practical: 36

Tutorial: 11

Field:

Course Aim

The aim of this course is to provide adequate knowledge in immunology and train the students in immunological techniques performed in a clinical laboratory.

Intended Learning Outcomes

At the end of the course unit students should be able to,

·         discuss the composition, function of immune system and regulation of immune response

·         outline the key components of the innate and acquired immune response

·         differentiate the different hypersensitive states

·         explain the basic principles of immunological techniques

·         outline the pathophysiology of autoimmune diseases

·         carryout basic and advanced immunological techniques used in a clinical laboratory

·         interpret the results of different immunological techniques     

Course content

Introduction of immunology: Cells & Tissues of the immune system, Immunity: definition and types, Vaccines: immunization schedules, principles of passive immunization and its significance in clinical medicine;  Mechanism of specific immune response, Mechanism of non  specific immune response, Major Histocompatibility Complex, Hypersensitivity; Immunologic Techniques: Immunoglobulin structure & Function, Nature of antigen, Antigen Antibody interaction and detection, Precipitation, Agglutination, Immunofluorescence, Neutralization tests, Complement fixation test, Coombs test,  Blotting Technique, Autoimmune Diseases

Teaching/Learning Methods

Lectures, Tutorials, SGDs, Practical

Assessment Strategy

Recommended Reading

Sheehan, C. (1997). Clinical immunology : principles and laboratory diagnosis. Philadelphia: Lippincott.

Male, D., Brostoff, J., Roth, D. and Roitt, I. (2012). Immunology : With STUDENT CONSULT Online Access. 8^th ed. London: Elsevier Health Sciences Uk.

Peter J. Delves, Seamus J. Martin, Dennis R. Burton and Ivan M. Roitt (2017). Roitt’s Essential Immunology. [online] 13^th ed. New York: John Wiley & Sons Inc.

Christine Dorresteyn Stevens and Miller, L.E. (2017). Clinical immunology & serology : a laboratory perspective. 4^th ed. Philadelphia: F.A. Davis Company.